Asthma sufferers who received vitamin D supplements for six months, in addition to their regular inhalers, could breathe a little easier than those who relied only on the inhalers, in a recent study in Iran.
The researchers say the results - if confirmed by larger studies - might help the many people who sometimes have troublesome asthma symptoms even though they use medication.
“It does build some on the growing amount of data that shows vitamin D might help those affected by asthma,” Dr. Mario Castro, who was not involved in the study, told Reuters Health.
But Castro, a professor of Pulmonary and Critical Care Medicine at Washington University School of Medicine in St. Louis, Missouri, pointed out that the researchers only measured patients’ lung function, and not whether or not their symptoms improved.
“Given that vitamin D is a relatively benign supplement,” the small improvement in lung function “would be worthwhile if it was confirmed with other improvements in asthma control,” he said, such as fewer symptoms or a reduced need for medication.
About one in 12 individuals, or 25 million people, have asthma in the U.S. alone. In the last decade, the number of people with asthma has grown by about 15 percent.
Higher rates of asthma in northern climates have led some researchers to suspect that less sunlight - and therefore less vitamin D - could be playing a role. Several studies have shown a link between low vitamin D levels and asthma.
The new study, by Dr. Saba Arshi at the Medical University of Tehran and colleagues, involved 130 children and adults with mild-to-moderate asthma.
Everyone received asthma medication in a dry powder inhaler (budesonide, sold in the U.S. as Pulmicort, or budesonide plus formoterol, sold in the U.S. as Symbicort).
In addition, half the group was randomly chosen to receive high doses of vitamin D for six months. The first dose, 100,000 units, was given by injection; then patients were instructed to take 50,000 units orally once a week.
After eight weeks, when the researchers measured the amount of air patients could exhale in one second, both groups had improved to roughly the same extent. But after 28 weeks, that amount had improved by about 20 percent in the patients who received vitamin D supplements, versus about 7 percent among those who only used the inhaler.
The authors did not respond to questions about the study, which was published in Annals of Allergy, Asthma and Immunology.