Global stocks edged lower along with the euro on Friday as the White House and US lawmakers planned to make a late effort to avoid the US fiscal cliff.
Elsewhere, expectations that Japan will inject new stimulus into its economy pushed the yen to a two-year low for a third day.
US President Barack Obama and Democratic and Republican lawmakers were scheduled to meet on Friday as the deadline looms for reaching a deal on the budget to avert massive tax increases and spending cuts which could drag the economy into recession and others around the world along with it.
The MSCI all-world share index was down 0.2 percent, while US stocks opened lower.
The Dow Jones industrial average was down 71.88 points, or 0.55 per cent, at 13,024.43. The Standard & Poors 500 Index was down 8.24 points, or 0.58 per cent, at 1,409.86. The Nasdaq Composite Index was down 15.22 points, or 0.51 per cent, at 2,970.68.
The pan-European FTSEurofirst 300 was down 0.5 per cent and was on track for a small weekly loss.
Going over the fiscal cliff allowing $600 billion of higher taxes and lower spending cuts to start coming into force in January would prevent US debt spilling beyond a $16.4 trillion agreed limit.
However, analysts fear that such measures could wipe as much as 4 per cent off the countrys growth rate, if left unchecked.
An agreement on the US budget would be viewed as positive for riskier currencies such as the euro, while a deadlock in the negotiations is deemed positive for the safe-haven and highly liquid dollar.
In the US bond market, benchmark Treasuries yields dropped to their lowest levels in two weeks as fiscal cliff concerns spurred demand for safe-haven bonds.